Funding: Shriners Foundation
Description. The goal of this project is to characterize neural control strategies underlying walking in children with cerebral palsy (CP) to inform the development of new therapeutic approaches. Recent studies have suggested that a significant contributor to the motor function deficit in children with CP may be impairment in the neural processing of tactile discrimination and proprioception information. The mechanisms associated with such sensory deficits, and how they impact motor control in individuals with CP, are unknown. The primary triad of sensory modalities that are crucial for healthy postural control are the visual, vestibular, and proprioceptive systems. We have developed innovative techniques to manipulate these sensory modalities, allowing investigation of how they support stable and flexible control of upright equilibrium during standing and walking. The long-term view is that this approach will identify mechanisms toward developing more effective sensorimotor rehabilitation paradigms for children with CP. The expected outcomes of this project include: 1) a better understanding of the relationship between sensory processing and functional mobility in individuals with CP; and 2) an elucidation of the effect of galvanic vestibular stimulation on individuals with CP.
Keywords: Visual, vestibular, locomotion, cerebral palsy